STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (452 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0469; Belongs to the pyruvate kinase family.
  
 0.991
pgk
Phosphoglycerate kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0126.
  
 
 0.990
pgm
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.990
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.984
fba
Fructose-bisphosphate aldolase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0191.
  
 0.977
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.970
pgiB
Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0166.
  
 0.965
gap
glyceraldehyde-3-P dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx;COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.936
gapA
Glyceraldehyde 3-phosphate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0057.
  
 
 0.936
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.925
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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