STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MS53_0041Putative ABC transporter ATP-binding protein; Identified by sequence similarity; putative; ORF located using Blastx;COG1136;TC:3.A.1.125.1. (608 aa)    
Predicted Functional Partners:
MS53_0613
Putative ABC transporter permease protein; Identified by sequence similarity; putative; ORF located using Blastx.
  
 
 0.994
MS53_0612
Putative ABC transporter ATP-binding protein; Identified by sequence similarity; putative; ORF located using Blastx;COG1136.
 
 
0.949
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.833
MS53_0294
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0477.
 
     0.789
sipS
Signal peptidase I; Identified by sequence similarity; putative; ORF located using Blastx;COG0681; Belongs to the peptidase S26 family.
  
  
 0.779
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
     
 0.775
MS53_0463
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;GeneMark;Blastx.
  
     0.706
MS53_0462
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
  
     0.698
MS53_0471
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0810.
 
     0.694
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
 
 0.678
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.