STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lplALipoate-protein ligase A; Identified by sequence similarity; putative; ORF located using Blastx;COG0095. (326 aa)    
Predicted Functional Partners:
pdhD
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249.
  
 0.979
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0508.
  
 0.957
pdhB
Pyruvate dehydrogenase E1 component, beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0022.
 
 
 0.945
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.927
MS53_0152
Putative mercuric reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG1249.
  
 
 0.890
prsA
Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462.
   
 
  0.848
MS53_0061
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
       0.818
MS53_0059
Hypothetical protein.
       0.809
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.731
parC
Identified by sequence similarity; putative; ORF located using Blastx;COG0188.
     
 0.728
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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