STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MS53_0110Putative DNase/RNase endonuclease; Identified by sequence similarity; putative; ORF located using Blastx;COG1525. (239 aa)    
Predicted Functional Partners:
MS53_0109
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
 
     0.828
MS53_0112
Identified by sequence similarity; putative; ORF located using Blastx;COG0742.
       0.782
MS53_0111
Putative tRNA (Uracil-5-) -methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx;COG2265; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.778
trmB
Putative methlytransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.773
pgk
Phosphoglycerate kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0126.
       0.703
MS53_0107
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG1554.
       0.508
pgmB
Beta-phosphoglucomutase; Identified by sequence similarity; putative; ORF located using Blastx;COG0637.
       0.501
MS53_0108
Identified by sequence similarity; putative; ORF located using Blastx;COG0366.
       0.501
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.484
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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