STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MS53_0152Putative mercuric reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG1249. (459 aa)    
Predicted Functional Partners:
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0508.
 
 0.995
pdhB
Pyruvate dehydrogenase E1 component, beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0022.
 
 0.994
pdhD
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249.
 
0.990
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.951
prsA
Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462.
   
 0.922
lplA
Lipoate-protein ligase A; Identified by sequence similarity; putative; ORF located using Blastx;COG0095.
  
 
 0.890
prpC
Protein phosphatase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0631.
   
 0.720
rpoD
DNA-directed RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.565
pepA-1
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
  
 0.535
ptsG
PTS system, glucose-specific IIABC component; Identified by sequence similarity; putative; ORF located using Blastx;COG1263;TC:4.A.1.1.2.
      
 0.530
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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