Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepALeucyl aminopeptidase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0260; Belongs to the peptidase M17 family. (460 aa)    
Predicted Functional Partners:
pepA-1
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
 
  
 
0.960
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.816
pepP
XAA-PRO aminopeptidase; Identified by sequence similarity; putative; ORF located using Blastx;COG0006.
  
 
 0.683
dgk
Deoxyguanosine kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG1428.
    
  0.504
MS53_0141
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG1428.
    
  0.504
MS53_0380
Putative deoxyguanosine kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG1428.
    
  0.504
pepO
Endopeptidase O; Identified by sequence similarity; putative; ORF located using Blastx;COG3590.
      
 0.470
MS53_0152
Putative mercuric reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG1249.
  
  
 0.443
pdhD
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249.
  
  
 0.428
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
     
 0.401
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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