STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0260; Belongs to the peptidase M17 family. (460 aa)    
Predicted Functional Partners:
pepA-1
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
 
  
 
0.960
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.814
pepP
XAA-PRO aminopeptidase; Identified by sequence similarity; putative; ORF located using Blastx;COG0006.
  
 
 0.706
dgk
Deoxyguanosine kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG1428.
    
  0.685
MS53_0141
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG1428.
    
  0.685
MS53_0380
Putative deoxyguanosine kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG1428.
    
  0.685
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.601
pdhD
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249.
  
  
 0.542
pepO
Endopeptidase O; Identified by sequence similarity; putative; ORF located using Blastx;COG3590.
      
 0.493
ptsI
Phosphoenolpyruvate-protein phosphatase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
      
 0.475
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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