STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (374 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component, beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0022.
 0.999
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0508.
 
 0.999
pdhD
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249.
  
 0.999
MS53_0152
Putative mercuric reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG1249.
  
 
 0.951
ldh
L-lactate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx;COG0039; Belongs to the LDH/MDH superfamily.
  
 
 0.938
lplA
Lipoate-protein ligase A; Identified by sequence similarity; putative; ORF located using Blastx;COG0095.
  
 
 0.927
pyk
Pyruvate kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0469; Belongs to the pyruvate kinase family.
  
 
 0.927
prsA
Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462.
  
 0.874
tktA
Transketolase; Identified by sequence similarity; putative; ORF located using Blastx;COG0021; Belongs to the transketolase family.
  
 
 0.874
fba
Fructose-bisphosphate aldolase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0191.
    
 0.854
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.