Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdhCDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0508. (294 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component, beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0022.
 
 0.999
pdhD
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249.
 0.999
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.998
MS53_0152
Putative mercuric reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG1249.
 
 0.972
pta
Phosphate acetyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer;GeneMark;Blastx;COG0280.
  
 
 0.934
prsA
Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462.
   
 0.896
lplA
Lipoate-protein ligase A; Identified by sequence similarity; putative; ORF located using Blastx;COG0095.
  
 0.808
prpC
Protein phosphatase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0631.
   
  0.736
MS53_0062
Putative acyl carrier protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0236.
  
 0.713
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
   
   0.619
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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