STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhDDihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249. (622 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 0.999
pdhB
Pyruvate dehydrogenase E1 component, beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0022.
 
 0.999
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0508.
 0.999
prsA
Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462.
  
 0.998
MS53_0152
Putative mercuric reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG1249.
 
0.990
lplA
Lipoate-protein ligase A; Identified by sequence similarity; putative; ORF located using Blastx;COG0095.
  
 0.979
prpC
Protein phosphatase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0631.
  
 0.973
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.960
trxA
Putative thioredoxin; Identified by sequence similarity; putative; ORF located using Blastx;COG0526.
  
 
 0.901
trxM
Thioredoxin; Identified by sequence similarity; putative; ORF located using Blastx;COG0526; Belongs to the thioredoxin family.
  
 
 0.901
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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