| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MS53_0528 | dnaN | MS53_0528 | MS53_0002 | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592. | 0.999 |
| MS53_0528 | gidB | MS53_0528 | MS53_0151 | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | Glucose inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.549 |
| MS53_0528 | glyA | MS53_0528 | MS53_0305 | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.621 |
| MS53_0528 | nfo | MS53_0528 | MS53_0125 | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | 0.619 |
| MS53_0528 | pheS | MS53_0528 | MS53_0308 | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | phenylalanyl-tRNA synthetase alpha chain; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.449 |
| MS53_0528 | pheT | MS53_0528 | MS53_0306 | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | Putative phenylalanyl-tRNA synthetase beta chain; Identified by sequence similarity; putative; ORF located using Blastx;COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.854 |
| MS53_0528 | ung | MS53_0528 | MS53_0307 | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | uracil-DNA glycosylase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0692; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.586 |
| dnaN | MS53_0528 | MS53_0002 | MS53_0528 | DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592. | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | 0.999 |
| dnaN | glyA | MS53_0002 | MS53_0305 | DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.468 |
| dnaN | pheS | MS53_0002 | MS53_0308 | DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592. | phenylalanyl-tRNA synthetase alpha chain; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.407 |
| dnaN | pheT | MS53_0002 | MS53_0306 | DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592. | Putative phenylalanyl-tRNA synthetase beta chain; Identified by sequence similarity; putative; ORF located using Blastx;COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.404 |
| dnaN | ung | MS53_0002 | MS53_0307 | DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592. | uracil-DNA glycosylase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0692; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.880 |
| gidB | MS53_0528 | MS53_0151 | MS53_0528 | Glucose inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | 0.549 |
| gidB | rpsM | MS53_0151 | MS53_0576 | Glucose inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. | 0.583 |
| gidB | ung | MS53_0151 | MS53_0307 | Glucose inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | uracil-DNA glycosylase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0692; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.600 |
| glyA | MS53_0528 | MS53_0305 | MS53_0528 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Identified by sequence similarity; putative; ORF located using Blastx;COG0258. | 0.621 |
| glyA | dnaN | MS53_0305 | MS53_0002 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592. | 0.468 |
| glyA | pheS | MS53_0305 | MS53_0308 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | phenylalanyl-tRNA synthetase alpha chain; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.861 |
| glyA | pheT | MS53_0305 | MS53_0306 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative phenylalanyl-tRNA synthetase beta chain; Identified by sequence similarity; putative; ORF located using Blastx;COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.897 |
| glyA | ung | MS53_0305 | MS53_0307 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | uracil-DNA glycosylase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0692; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.829 |