Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uppUracil phosphoribosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx;COG0035; Belongs to the UPRTase family. (206 aa)    
Predicted Functional Partners:
pyrH
Uridylate kinase smbA; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.942
deoA
Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213.
    
 0.937
rpiB
Ribose 5-phosphate isomerase B; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0698.
 
    0.901
MS53_0310
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
       0.818
leuS
leucyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.812
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.772
lon
Heat shock ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity).
   
   0.749
pheS
phenylalanyl-tRNA synthetase alpha chain; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0016; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
     
 0.630
ung
uracil-DNA glycosylase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0692; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
     
 0.605
cmk
Cytidylate kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0283.
  
 
 0.597
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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