Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
gyrADNA gyrase subunit A; Identified by sequence similarity; putative; ORF located using Glimmer;GeneMark;Blastx;COG0188. (865 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; Identified by sequence similarity; putative; ORF located using Glimmer;GeneMark;Blastx;COG0187.
 
 
 0.987
parE
Identified by sequence similarity; putative; ORF located using Blastx;COG0187.
 
 
 0.986
parC
Identified by sequence similarity; putative; ORF located using Blastx;COG0188.
  
  
0.704
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  
 0.675
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.674
rplV
50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
   
  
 0.674
folD
Methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.660
metG
methionyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0143; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.657
MS53_0324
Hypothetical protein.
  
  
 0.637
MS53_0528
Identified by sequence similarity; putative; ORF located using Blastx;COG0258.
  
  
 0.605
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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