| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MS53_0391 | cls | MS53_0391 | MS53_0393 | Putative ABC transporter ATP-binding; Identified by sequence similarity; putative; ORF located using Blastx;COG2274;TC:3.A.1.112.4. | Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG1502. | 0.547 |
| MS53_0391 | ptsH | MS53_0391 | MS53_0394 | Putative ABC transporter ATP-binding; Identified by sequence similarity; putative; ORF located using Blastx;COG2274;TC:3.A.1.112.4. | Phophocarrier protein HPr; Identified by sequence similarity; putative; ORF located using Blastx;COG1925. | 0.440 |
| MS53_0391 | rpiB | MS53_0391 | MS53_0392 | Putative ABC transporter ATP-binding; Identified by sequence similarity; putative; ORF located using Blastx;COG2274;TC:3.A.1.112.4. | Ribose 5-phosphate isomerase B; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0698. | 0.615 |
| MS53_0664 | rpiB | MS53_0664 | MS53_0392 | Putative GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Ribose 5-phosphate isomerase B; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0698. | 0.730 |
| cls | MS53_0391 | MS53_0393 | MS53_0391 | Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG1502. | Putative ABC transporter ATP-binding; Identified by sequence similarity; putative; ORF located using Blastx;COG2274;TC:3.A.1.112.4. | 0.547 |
| cls | glyA | MS53_0393 | MS53_0305 | Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG1502. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.442 |
| cls | ptsH | MS53_0393 | MS53_0394 | Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG1502. | Phophocarrier protein HPr; Identified by sequence similarity; putative; ORF located using Blastx;COG1925. | 0.648 |
| cls | rpiB | MS53_0393 | MS53_0392 | Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG1502. | Ribose 5-phosphate isomerase B; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0698. | 0.778 |
| deoB | prsA | MS53_0083 | MS53_0150 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462. | 0.912 |
| deoB | rpe | MS53_0083 | MS53_0119 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Ribulose-phosphate 3-epimerase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0036. | 0.472 |
| deoB | rpiB | MS53_0083 | MS53_0392 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Ribose 5-phosphate isomerase B; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0698. | 0.943 |
| deoB | tktA | MS53_0083 | MS53_0181 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Transketolase; Identified by sequence similarity; putative; ORF located using Blastx;COG0021; Belongs to the transketolase family. | 0.913 |
| glyA | cls | MS53_0305 | MS53_0393 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG1502. | 0.442 |
| glyA | rpiB | MS53_0305 | MS53_0392 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ribose 5-phosphate isomerase B; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0698. | 0.926 |
| glyA | upp | MS53_0305 | MS53_0309 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx;COG0035; Belongs to the UPRTase family. | 0.772 |
| prsA | deoB | MS53_0150 | MS53_0083 | Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.912 |
| prsA | rpe | MS53_0150 | MS53_0119 | Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462. | Ribulose-phosphate 3-epimerase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0036. | 0.559 |
| prsA | rpiB | MS53_0150 | MS53_0392 | Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462. | Ribose 5-phosphate isomerase B; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0698. | 0.945 |
| prsA | tktA | MS53_0150 | MS53_0181 | Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0462. | Transketolase; Identified by sequence similarity; putative; ORF located using Blastx;COG0021; Belongs to the transketolase family. | 0.949 |
| ptsH | MS53_0391 | MS53_0394 | MS53_0391 | Phophocarrier protein HPr; Identified by sequence similarity; putative; ORF located using Blastx;COG1925. | Putative ABC transporter ATP-binding; Identified by sequence similarity; putative; ORF located using Blastx;COG2274;TC:3.A.1.112.4. | 0.440 |