Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
clsCardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG1502. (504 aa)    
Predicted Functional Partners:
rpiB
Ribose 5-phosphate isomerase B; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0698.
       0.778
obg
GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
  
 0.705
ptsH
Phophocarrier protein HPr; Identified by sequence similarity; putative; ORF located using Blastx;COG1925.
     
 0.648
MS53_0073
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0658;TC:3.A.11.1.1.
   
 
 0.633
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.621
MS53_0391
Putative ABC transporter ATP-binding; Identified by sequence similarity; putative; ORF located using Blastx;COG2274;TC:3.A.1.112.4.
       0.547
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by sequence similarity; putative; ORF located using Blastx;COG0204.
   
 0.490
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
       0.486
era
GTP-binding protein ERA; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.474
MS53_0390
Hypothetical protein.
       0.443
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
Server load: low (14%) [HD]