Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ptsHPhophocarrier protein HPr; Identified by sequence similarity; putative; ORF located using Blastx;COG1925. (87 aa)    
Predicted Functional Partners:
ptsI
Phosphoenolpyruvate-protein phosphatase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 0.998
ptsG
PTS system, glucose-specific IIABC component; Identified by sequence similarity; putative; ORF located using Blastx;COG1263;TC:4.A.1.1.2.
  
 0.986
sgaA
Pentitol phosphotransferase enzyme II, A component; Identified by sequence similarity; putative; ORF located using Blastx;COG1762;TC:4.A.7.1.1.
  
 
 0.923
sgaA-1
PTS system, IIA component; Identified by sequence similarity; putative; ORF located using Blastx;COG1762.
  
 
 0.923
MS53_0027
Putative PTS system, IIB component; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG3414.
    
  0.909
MS53_0682
Putative PTS system, IIB component; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG3414.
    
  0.909
sgaT-1
Transport protein SgaT; Identified by sequence similarity; putative; ORF located using Blastx;COG3037;TC:4.A.7.1.1.
    
  0.908
sgaT-2
Transport protein SgaT; Identified by sequence similarity; putative; ORF located using Blastx;COG3037;TC:4.A.7.1.1.
    
  0.908
MS53_0127
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG1609.
   
 
 0.902
cls
Cardiolipin synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG1502.
     
 0.648
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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