| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MS53_0449 | deoA | MS53_0449 | MS53_0446 | Hypothetical protein. | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | 0.584 |
| MS53_0449 | deoC | MS53_0449 | MS53_0445 | Hypothetical protein. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.597 |
| MS53_0449 | deoD | MS53_0449 | MS53_0447 | Hypothetical protein. | Purine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0813. | 0.546 |
| MS53_0449 | fpg | MS53_0449 | MS53_0448 | Hypothetical protein. | Foramidopyrimidine DNA gycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.807 |
| cdd | deoA | MS53_0388 | MS53_0446 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | 0.948 |
| cdd | deoC | MS53_0388 | MS53_0445 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.461 |
| cdd | deoD | MS53_0388 | MS53_0447 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Purine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0813. | 0.950 |
| cdd | era | MS53_0388 | MS53_0387 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | GTP-binding protein ERA; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.949 |
| cdd | tdk | MS53_0388 | MS53_0521 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine kinase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG1435. | 0.921 |
| comEB | deoA | MS53_0396 | MS53_0446 | Deoxycytidylate deaminase fusion protein; Identified by sequence similarity; putative; ORF located using Blastx;COG2131. | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | 0.560 |
| comEB | tdk | MS53_0396 | MS53_0521 | Deoxycytidylate deaminase fusion protein; Identified by sequence similarity; putative; ORF located using Blastx;COG2131. | Thymidine kinase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG1435. | 0.930 |
| deoA | MS53_0449 | MS53_0446 | MS53_0449 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | Hypothetical protein. | 0.584 |
| deoA | cdd | MS53_0446 | MS53_0388 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.948 |
| deoA | comEB | MS53_0446 | MS53_0396 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | Deoxycytidylate deaminase fusion protein; Identified by sequence similarity; putative; ORF located using Blastx;COG2131. | 0.560 |
| deoA | deoB | MS53_0446 | MS53_0083 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.924 |
| deoA | deoC | MS53_0446 | MS53_0445 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.968 |
| deoA | deoD | MS53_0446 | MS53_0447 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | Purine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0813. | 0.990 |
| deoA | era | MS53_0446 | MS53_0387 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | GTP-binding protein ERA; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.583 |
| deoA | fpg | MS53_0446 | MS53_0448 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | Foramidopyrimidine DNA gycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.551 |
| deoA | tdk | MS53_0446 | MS53_0521 | Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213. | Thymidine kinase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG1435. | 0.936 |