Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MS53_0449Hypothetical protein. (180 aa)    
Predicted Functional Partners:
fpg
Foramidopyrimidine DNA gycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.809
gpsA
Glycerol-3-phosphate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx;COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
   0.773
MS53_0109
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
 
     0.654
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
   0.625
MS53_0090
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG1295.
 
    0.603
deoA
Pyrimidine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0213.
       0.587
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.570
deoD
Purine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0813.
       0.546
MS53_0511
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0687.
  
     0.532
MS53_0158
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;GeneMark;Blastx.
  
     0.525
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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