Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ldhL-lactate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx;COG0039; Belongs to the LDH/MDH superfamily. (323 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0469; Belongs to the pyruvate kinase family.
  
 0.987
pdhB
Pyruvate dehydrogenase E1 component, beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0022.
  
 0.980
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.926
pgiB
Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0166.
  
 0.896
tktA
Transketolase; Identified by sequence similarity; putative; ORF located using Blastx;COG0021; Belongs to the transketolase family.
  
 0.867
fba
Fructose-bisphosphate aldolase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG0191.
   
 
 0.859
MS53_0062
Putative acyl carrier protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0236.
  
 
 0.819
pdhD
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249.
  
 0.815
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
     
  0.800
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.793
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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