STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIThiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (376 aa)    
Predicted Functional Partners:
MS53_0503
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0561.
  
    0.780
MS53_0504
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
       0.773
pheT
Putative phenylalanyl-tRNA synthetase beta chain; Identified by sequence similarity; putative; ORF located using Blastx;COG0072; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.537
smc
Putative ABC transporter ATP-binding protein P115-like protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
   
  
 0.490
truB
tRNA pseudouridine synthase B; Identified by sequence similarity; putative; ORF located using Blastx;COG0130; Belongs to the pseudouridine synthase TruB family.
   
  
 0.481
hemK
Protoporphirogen oxidase HemK; Identified by sequence similarity; putative; ORF located using Blastx;COG2890.
   
  
 0.477
pknB
Serine/threonine-protein kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0515.
      
 0.472
rpmH
50S ribosomal protein L34; Identified by sequence similarity; putative; ORF located using Blastx;COG0230; Belongs to the bacterial ribosomal protein bL34 family.
      
 0.457
MS53_0501
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
       0.454
MS53_0502
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
       0.454
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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