STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ktrAPutative potassium uptake protein KtrA; Identified by sequence similarity; putative; ORF located using Blastx;COG0569;TC:2.A.38.4.3. (231 aa)    
Predicted Functional Partners:
ktrB
Putative potassium uptake protein KtrB; Identified by sequence similarity; putative; ORF located using Blastx;COG0168;TC:2.A.38.4.2.
 
 
 0.999
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
       0.646
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
      
 0.617
potB
Spermidine/putrescine ABC transporter permease protein PotB; Identified by sequence similarity; putative; ORF located using Blastx;COG1176;TC:3.A.1.11.1.
  
  
 0.601
smc
Putative ABC transporter ATP-binding protein P115-like protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
  
 0.594
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.590
MS53_0435
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG1970.
     
 0.582
rpmH
50S ribosomal protein L34; Identified by sequence similarity; putative; ORF located using Blastx;COG0230; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.575
pknB
Serine/threonine-protein kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0515.
  
  
 0.573
dnaJ
Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
 
 0.573
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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