Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
whiAConserved hypothetical protein; Involved in cell division and chromosome segregation. (284 aa)    
Predicted Functional Partners:
rpoD
DNA-directed RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.791
rpoC
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.776
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.776
polC
DNA polymerase III alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
     0.676
ktrA
Putative potassium uptake protein KtrA; Identified by sequence similarity; putative; ORF located using Blastx;COG0569;TC:2.A.38.4.3.
  
    0.647
ktrB
Putative potassium uptake protein KtrB; Identified by sequence similarity; putative; ORF located using Blastx;COG0168;TC:2.A.38.4.2.
       0.645
pknB
Serine/threonine-protein kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0515.
     
 0.568
tdk
Thymidine kinase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG1435.
       0.567
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.566
MS53_0661
Putative ABC transporter permease protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0619.
 
     0.554
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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