STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MS53_0525Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. (291 aa)    
Predicted Functional Partners:
dnaB
Replicative DNA helicase; Identified by sequence similarity; putative; ORF located using Blastx;COG0305.
  
 
 0.990
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
    0.811
MS53_0528
Identified by sequence similarity; putative; ORF located using Blastx;COG0258.
     
 0.766
MS53_0526
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG3611.
  
  
 0.734
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.611
dnaE
DNA polymerase III alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0587.
     
 0.604
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.592
MS53_0527
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0237.
     
 0.535
ssb
Single stranded binding protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0629.
     
 0.409
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.