STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MS53_0528Identified by sequence similarity; putative; ORF located using Blastx;COG0258. (294 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592.
  
 0.999
recA
Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.999
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.989
fpg
Foramidopyrimidine DNA gycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.957
dinP
DNA polymerase IV; Identified by sequence similarity; putative; ORF located using Blastx;COG0389.
  
 0.941
dnaE
DNA polymerase III alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0587.
  
 
 0.934
MS53_0527
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0237.
  
  
 0.933
MS53_0291
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0017.
  
 0.903
asnS
asparaginyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG0017.
  
 0.903
pcrA
Atp-dependent helicase; Identified by sequence similarity; putative; ORF located using Blastx;COG0210.
   
 
 0.879
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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