| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MS53_0594 | dnaJ | MS53_0594 | MS53_0593 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.405 |
| MS53_0594 | rluD | MS53_0594 | MS53_0595 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.746 |
| MS53_0594 | trxB | MS53_0594 | MS53_0596 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx. | Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG0492. | 0.631 |
| dnaJ | MS53_0594 | MS53_0593 | MS53_0594 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx. | 0.405 |
| dnaJ | metG | MS53_0593 | MS53_0303 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | methionyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0143; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.553 |
| dnaJ | pdhD | MS53_0593 | MS53_0275 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249. | 0.587 |
| dnaJ | rluD | MS53_0593 | MS53_0595 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.823 |
| dnaJ | secD | MS53_0593 | MS53_0167 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.657 |
| dnaJ | trxB | MS53_0593 | MS53_0596 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG0492. | 0.562 |
| lgt | rluD | MS53_0597 | MS53_0595 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.517 |
| lgt | secD | MS53_0597 | MS53_0167 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.658 |
| lgt | trxB | MS53_0597 | MS53_0596 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG0492. | 0.571 |
| metG | dnaJ | MS53_0303 | MS53_0593 | methionyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0143; Belongs to the class-I aminoacyl-tRNA synthetase family. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.553 |
| metG | pdhD | MS53_0303 | MS53_0275 | methionyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0143; Belongs to the class-I aminoacyl-tRNA synthetase family. | Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249. | 0.726 |
| metG | secD | MS53_0303 | MS53_0167 | methionyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0143; Belongs to the class-I aminoacyl-tRNA synthetase family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.670 |
| metG | trxB | MS53_0303 | MS53_0596 | methionyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0143; Belongs to the class-I aminoacyl-tRNA synthetase family. | Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG0492. | 0.615 |
| nifS | trxB | MS53_0322 | MS53_0596 | Nitrogen fixation protein NifS; Identified by sequence similarity; putative; ORF located using Blastx;COG0520. | Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG0492. | 0.910 |
| pdhD | dnaJ | MS53_0275 | MS53_0593 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.587 |
| pdhD | metG | MS53_0275 | MS53_0303 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249. | methionyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0143; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.726 |
| pdhD | trxA | MS53_0275 | MS53_0645 | Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249. | Putative thioredoxin; Identified by sequence similarity; putative; ORF located using Blastx;COG0526. | 0.713 |
