| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MS53_0360 | MS53_0599 | MS53_0360 | MS53_0599 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | 0.900 |
| MS53_0360 | MS53_0709 | MS53_0360 | MS53_0709 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.900 |
| MS53_0360 | ffh | MS53_0360 | MS53_0021 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.900 |
| MS53_0360 | ftsY | MS53_0360 | MS53_0145 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.900 |
| MS53_0360 | secA | MS53_0360 | MS53_0128 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.900 |
| MS53_0360 | secD | MS53_0360 | MS53_0167 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.900 |
| MS53_0360 | secY | MS53_0360 | MS53_0581 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase secy subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.900 |
| MS53_0599 | MS53_0360 | MS53_0599 | MS53_0360 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | 0.900 |
| MS53_0599 | MS53_0709 | MS53_0599 | MS53_0709 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.993 |
| MS53_0599 | atpE | MS53_0599 | MS53_0410 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.964 |
| MS53_0599 | ffh | MS53_0599 | MS53_0021 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.956 |
| MS53_0599 | ftsY | MS53_0599 | MS53_0145 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.957 |
| MS53_0599 | rnpA | MS53_0599 | MS53_0600 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.973 |
| MS53_0599 | rpsE | MS53_0599 | MS53_0626 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.917 |
| MS53_0599 | secA | MS53_0599 | MS53_0128 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.960 |
| MS53_0599 | secD | MS53_0599 | MS53_0167 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.999 |
| MS53_0599 | secY | MS53_0599 | MS53_0581 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | Preprotein translocase secy subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.997 |
| MS53_0709 | MS53_0360 | MS53_0709 | MS53_0360 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0690; Belongs to the SecE/SEC61-gamma family. | 0.900 |
| MS53_0709 | MS53_0599 | MS53_0709 | MS53_0599 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0706;TC:2.A.9.3.2. | 0.993 |
| MS53_0709 | ffh | MS53_0709 | MS53_0021 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.984 |