Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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Textmining
[Homology]
Score
trxMThioredoxin; Identified by sequence similarity; putative; ORF located using Blastx;COG0526; Belongs to the thioredoxin family. (101 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Blastx;COG0492.
  
 
 0.846
nrdE
Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.800
pdhD
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark;Blastx;COG1249.
  
 
 0.713
pgm
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
    0.535
MS53_0657
Putative ABC transporter ATP-binding protein; Identified by sequence similarity; putative; ORF located using Blastx;COG1131.
       0.510
MS53_0658
Putative ABC transporter; Identified by sequence similarity; putative; ORF located using Blastx;COG0842.
       0.510
nrdF
Ribonucleoside-diphosphate reductase beta chain; Identified by sequence similarity; putative; ORF located using Blastx;COG0208.
  
 
 0.489
tufA
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
    
 
 0.475
MS53_0039
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0480.
   
 
 0.454
fusA
Elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.454
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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