STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (169 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.973
hpt
Hypoxanthine-guanine phosphoribosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx;COG0634; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 0.970
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.940
deoD
Purine-nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Blastx;COG0813.
    
 0.936
MS53_0141
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer;Blastx;COG1428.
  
 
 0.910
infB
Putative translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
    0.823
MS53_0528
Identified by sequence similarity; putative; ORF located using Blastx;COG0258.
     
 0.585
metG
methionyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx;COG0143; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.552
nusA
N-utilization substance protein A; Identified by sequence similarity; putative; ORF located using Blastx;COG0195.
  
    0.546
MS53_0191
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0591;TC:2.A.21.5.2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.468
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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