| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaA | dnaB | PAM_001 | PAM_013 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.795 |
| dnaA | dnaC | PAM_001 | PAM_672 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA replication protein; Identified by sequence similarity; putative. | 0.731 |
| dnaA | dnaG-5 | PAM_001 | PAM_627 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.460 |
| dnaA | prfA | PAM_001 | PAM_014 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Protein chain release factor A; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.424 |
| dnaA | rplI | PAM_001 | PAM_012 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Exopolyphosphatase-related protein; Binds to the 23S rRNA. | 0.563 |
| dnaB | dnaA | PAM_013 | PAM_001 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.795 |
| dnaB | dnaC | PAM_013 | PAM_672 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA replication protein; Identified by sequence similarity; putative. | 0.792 |
| dnaB | dnaG | PAM_013 | PAM_524 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; Identified by sequence similarity; putative. | 0.845 |
| dnaB | dnaG-2 | PAM_013 | PAM_549 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; Identified by sequence similarity; putative. | 0.845 |
| dnaB | dnaG-3 | PAM_013 | PAM_569 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; Identified by sequence similarity; putative. | 0.845 |
| dnaB | dnaG-4 | PAM_013 | PAM_572 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; Identified by sequence similarity; putative. | 0.845 |
| dnaB | dnaG-5 | PAM_013 | PAM_627 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.876 |
| dnaB | dnaG-7 | PAM_013 | PAM_685 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; Identified by sequence similarity; putative. | 0.845 |
| dnaB | prfA | PAM_013 | PAM_014 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Protein chain release factor A; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.832 |
| dnaB | rplI | PAM_013 | PAM_012 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Exopolyphosphatase-related protein; Binds to the 23S rRNA. | 0.945 |
| dnaC | dnaA | PAM_672 | PAM_001 | DNA replication protein; Identified by sequence similarity; putative. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.731 |
| dnaC | dnaB | PAM_672 | PAM_013 | DNA replication protein; Identified by sequence similarity; putative. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.792 |
| dnaC | dnaG-5 | PAM_672 | PAM_627 | DNA replication protein; Identified by sequence similarity; putative. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.464 |
| dnaC | rplI | PAM_672 | PAM_012 | DNA replication protein; Identified by sequence similarity; putative. | Exopolyphosphatase-related protein; Binds to the 23S rRNA. | 0.663 |
| dnaG | dnaB | PAM_524 | PAM_013 | DNA primase; Identified by sequence similarity; putative. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.845 |