| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PAM_632 | polA | PAM_632 | PAM_675 | Conserved hypothetical protein; Identified by sequence similarity; putative; Belongs to the ArsC family. | DNA polymerase I; Identified by sequence similarity; putative. | 0.568 |
| PAM_632 | znuA | PAM_632 | PAM_092 | Conserved hypothetical protein; Identified by sequence similarity; putative; Belongs to the ArsC family. | ABC-type Mn/Zn transport system, periplasmic Mn/Zn-binding protein; Identified by sequence similarity; putative. | 0.412 |
| PAM_632 | znuC | PAM_632 | PAM_093 | Conserved hypothetical protein; Identified by sequence similarity; putative; Belongs to the ArsC family. | ABC-type Mn/Zn transport system, ATPase; Identified by sequence similarity; putative. | 0.461 |
| cbiQ | potB | PAM_180 | PAM_660 | ABC-type cobalt transport system, permease; Identified by sequence similarity; putative. | ABC-type spermidine/putrescine transport system, permease component I; Identified by sequence similarity; putative. | 0.407 |
| cbiQ | znuA | PAM_180 | PAM_092 | ABC-type cobalt transport system, permease; Identified by sequence similarity; putative. | ABC-type Mn/Zn transport system, periplasmic Mn/Zn-binding protein; Identified by sequence similarity; putative. | 0.455 |
| cbiQ | znuB | PAM_180 | PAM_094 | ABC-type cobalt transport system, permease; Identified by sequence similarity; putative. | ABC-type Mn/Zn transport system, permease; Identified by sequence similarity; putative. | 0.485 |
| cbiQ | znuC | PAM_180 | PAM_093 | ABC-type cobalt transport system, permease; Identified by sequence similarity; putative. | ABC-type Mn/Zn transport system, ATPase; Identified by sequence similarity; putative. | 0.565 |
| dnaJ | polA | PAM_703 | PAM_675 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | DNA polymerase I; Identified by sequence similarity; putative. | 0.808 |
| dnaJ | potB | PAM_703 | PAM_660 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | ABC-type spermidine/putrescine transport system, permease component I; Identified by sequence similarity; putative. | 0.680 |
| dnaJ | sodA | PAM_703 | PAM_442 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.856 |
| dnaJ | topA | PAM_703 | PAM_279 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.808 |
| dnaJ | znuC | PAM_703 | PAM_093 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | ABC-type Mn/Zn transport system, ATPase; Identified by sequence similarity; putative. | 0.522 |
| polA | PAM_632 | PAM_675 | PAM_632 | DNA polymerase I; Identified by sequence similarity; putative. | Conserved hypothetical protein; Identified by sequence similarity; putative; Belongs to the ArsC family. | 0.568 |
| polA | dnaJ | PAM_675 | PAM_703 | DNA polymerase I; Identified by sequence similarity; putative. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.808 |
| polA | potB | PAM_675 | PAM_660 | DNA polymerase I; Identified by sequence similarity; putative. | ABC-type spermidine/putrescine transport system, permease component I; Identified by sequence similarity; putative. | 0.435 |
| polA | rpmE | PAM_675 | PAM_105 | DNA polymerase I; Identified by sequence similarity; putative. | Ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.753 |
| polA | sodA | PAM_675 | PAM_442 | DNA polymerase I; Identified by sequence similarity; putative. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.658 |
| polA | topA | PAM_675 | PAM_279 | DNA polymerase I; Identified by sequence similarity; putative. | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.945 |
| polA | znuA | PAM_675 | PAM_092 | DNA polymerase I; Identified by sequence similarity; putative. | ABC-type Mn/Zn transport system, periplasmic Mn/Zn-binding protein; Identified by sequence similarity; putative. | 0.456 |
| polA | znuB | PAM_675 | PAM_094 | DNA polymerase I; Identified by sequence similarity; putative. | ABC-type Mn/Zn transport system, permease; Identified by sequence similarity; putative. | 0.524 |