Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (835 aa)    
Predicted Functional Partners:
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
 0.998
secE
Preprotein translocase subunit SecE; Identified by sequence similarity; putative; Belongs to the SecE/SEC61-gamma family.
    
 0.994
yidC
Preprotein translocase subunit YidC; Identified by sequence similarity; putative.
  
 
 0.987
ffh
Signal recognition particle GTPase; Identified by sequence similarity; putative.
    
 0.983
ftsY
Signal recognition particle-docking protein; Identified by sequence similarity; putative.
    
 0.982
prfB
Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
  
  
 0.941
rplV
Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
  
 
 0.937
polA
DNA polymerase I; Identified by sequence similarity; putative.
  
  
 0.877
tufB
Translation elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
  
 0.875
leuS
leucyl-tRNA synthetase; Identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.863
Your Current Organism:
Onion yellows
NCBI taxonomy Id: 262768
Other names: O. yellows phytoplasma OY-M, Onion yellows phytoplasma OY-M
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