acoB protein (Onion yellows) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

acoB

Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit; Identified by sequence similarity; putative. (324 aa)

Predicted Functional Partners:

acoA

0.999

aceF

0.999

lpd

0.999

sfcA

0.977

pykF

0.950

groEL

0.943

pgi

0.906

dnaK

0.897

fba

0.895

lon

0.790

Your Current Organism:

Onion yellows

NCBI taxonomy Id: 262768
Other names: O. yellows phytoplasma OY-M, Onion yellows phytoplasma OY-M

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aceF	acoA	PAM_602	PAM_600	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.999
aceF	acoB	PAM_602	PAM_601	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit; Identified by sequence similarity; putative.	0.999
aceF	dnaK	PAM_602	PAM_704	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.831
aceF	fba	PAM_602	PAM_172	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Fructose/tagatose bisphosphate aldolase; Identified by sequence similarity; putative.	0.496
aceF	groEL	PAM_602	PAM_121	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.803
aceF	lon	PAM_602	PAM_448	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	0.830
aceF	lpd	PAM_602	PAM_603	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Fatty acid/phospholipid biosynthesis enzyme; Identified by sequence similarity; putative.	0.999
aceF	pgi	PAM_602	PAM_283	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Glucose-6-phosphate isomerase; Identified by sequence similarity; putative.	0.575
aceF	pykF	PAM_602	PAM_287	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Pyruvate kinase; Identified by sequence similarity; putative; Belongs to the pyruvate kinase family.	0.537
aceF	sfcA	PAM_602	PAM_721	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	Malic enzyme; Identified by sequence similarity; putative.	0.619
acoA	aceF	PAM_600	PAM_602	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	0.999
acoA	acoB	PAM_600	PAM_601	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit; Identified by sequence similarity; putative.	0.999
acoA	dnaK	PAM_600	PAM_704	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.474
acoA	fba	PAM_600	PAM_172	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	Fructose/tagatose bisphosphate aldolase; Identified by sequence similarity; putative.	0.904
acoA	lpd	PAM_600	PAM_603	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	Fatty acid/phospholipid biosynthesis enzyme; Identified by sequence similarity; putative.	0.997
acoA	pgi	PAM_600	PAM_283	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	Glucose-6-phosphate isomerase; Identified by sequence similarity; putative.	0.906
acoA	pykF	PAM_600	PAM_287	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	Pyruvate kinase; Identified by sequence similarity; putative; Belongs to the pyruvate kinase family.	0.957
acoA	sfcA	PAM_600	PAM_721	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	Malic enzyme; Identified by sequence similarity; putative.	0.960
acoB	aceF	PAM_601	PAM_602	Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit; Identified by sequence similarity; putative.	Dihydrolipoamide acyltransferase; Identified by sequence similarity; putative.	0.999
acoB	acoA	PAM_601	PAM_600	Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit; Identified by sequence similarity; putative.	Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.999