STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCF35114.1Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains. (323 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.998
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.906
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
     0.866
coaX
Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
   
 0.680
SCF35106.1
SAM-dependent methyltransferase, MidA family.
       0.596
SCF35144.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
   
 0.557
lysS-2
lysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.506
nuoD-2
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
       0.491
SCE74323.1
Ketopantoate reductase.
    
  0.446
SCF35137.1
Septum formation.
       0.443
Your Current Organism:
Micromonospora mirobrigensis
NCBI taxonomy Id: 262898
Other names: DSM 44830, JCM 13240, LMG 22229, LMG:22229, M. mirobrigensis, Micromonospora mirobrigensis Trujillo et al. 2005, Micromonospora sp. WA201, NBRC 101890, strain WA201
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