node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEB42050.1 | AEB45808.1 | VAB18032_04620 | VAB18032_23550 | ATPase; COG2217 Cation transport ATPase. | COG2119 Predicted membrane protein. | 0.410 |
AEB45807.1 | AEB45808.1 | VAB18032_23545 | VAB18032_23550 | COG4828 Predicted membrane protein. | COG2119 Predicted membrane protein. | 0.624 |
AEB45808.1 | AEB42050.1 | VAB18032_23550 | VAB18032_04620 | COG2119 Predicted membrane protein. | ATPase; COG2217 Cation transport ATPase. | 0.410 |
AEB45808.1 | AEB45807.1 | VAB18032_23550 | VAB18032_23545 | COG2119 Predicted membrane protein. | COG4828 Predicted membrane protein. | 0.624 |
AEB45808.1 | egtA | VAB18032_23550 | VAB18032_23570 | COG2119 Predicted membrane protein. | Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.418 |
AEB45808.1 | egtB | VAB18032_23550 | VAB18032_23565 | COG2119 Predicted membrane protein. | Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.418 |
AEB45808.1 | egtC | VAB18032_23550 | VAB18032_23560 | COG2119 Predicted membrane protein. | Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.421 |
AEB45808.1 | egtD | VAB18032_23550 | VAB18032_23555 | COG2119 Predicted membrane protein. | Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.418 |
egtA | AEB45808.1 | VAB18032_23570 | VAB18032_23550 | Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | COG2119 Predicted membrane protein. | 0.418 |
egtA | egtB | VAB18032_23570 | VAB18032_23565 | Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.994 |
egtA | egtC | VAB18032_23570 | VAB18032_23560 | Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.973 |
egtA | egtD | VAB18032_23570 | VAB18032_23555 | Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.975 |
egtB | AEB45808.1 | VAB18032_23565 | VAB18032_23550 | Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | COG2119 Predicted membrane protein. | 0.418 |
egtB | egtA | VAB18032_23565 | VAB18032_23570 | Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.994 |
egtB | egtC | VAB18032_23565 | VAB18032_23560 | Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.999 |
egtB | egtD | VAB18032_23565 | VAB18032_23555 | Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.999 |
egtC | AEB45808.1 | VAB18032_23560 | VAB18032_23550 | Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | COG2119 Predicted membrane protein. | 0.421 |
egtC | egtA | VAB18032_23560 | VAB18032_23570 | Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.973 |
egtC | egtB | VAB18032_23560 | VAB18032_23565 | Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.999 |
egtC | egtD | VAB18032_23560 | VAB18032_23555 | Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.993 |