node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEB43187.1 | AEB47625.1 | VAB18032_10345 | VAB18032_02705 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.978 |
AEB43187.1 | AEB47626.1 | VAB18032_10345 | VAB18032_02710 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.608 |
AEB43187.1 | nadA | VAB18032_10345 | VAB18032_27291 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.670 |
AEB43187.1 | nadD | VAB18032_10345 | VAB18032_28466 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.970 |
AEB46388.1 | hisB | VAB18032_26556 | VAB18032_26706 | COG0067 Glutamate synthase domain 1. | COG0131 Imidazoleglycerol-phosphate dehydratase. | 0.780 |
AEB46388.1 | nadA | VAB18032_26556 | VAB18032_27291 | COG0067 Glutamate synthase domain 1. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.650 |
AEB46388.1 | nadD | VAB18032_26556 | VAB18032_28466 | COG0067 Glutamate synthase domain 1. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.408 |
AEB46388.1 | rho | VAB18032_26556 | VAB18032_29671 | COG0067 Glutamate synthase domain 1. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.409 |
AEB46530.1 | nadA | VAB18032_27286 | VAB18032_27291 | COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.655 |
AEB47625.1 | AEB43187.1 | VAB18032_02705 | VAB18032_10345 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.978 |
AEB47625.1 | AEB47626.1 | VAB18032_02705 | VAB18032_02710 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.999 |
AEB47625.1 | hisB | VAB18032_02705 | VAB18032_26706 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | COG0131 Imidazoleglycerol-phosphate dehydratase. | 0.432 |
AEB47625.1 | nadA | VAB18032_02705 | VAB18032_27291 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.999 |
AEB47625.1 | nadD | VAB18032_02705 | VAB18032_28466 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.968 |
AEB47625.1 | rho | VAB18032_02705 | VAB18032_29671 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.422 |
AEB47626.1 | AEB43187.1 | VAB18032_02710 | VAB18032_10345 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.608 |
AEB47626.1 | AEB47625.1 | VAB18032_02710 | VAB18032_02705 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.999 |
AEB47626.1 | nadA | VAB18032_02710 | VAB18032_27291 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.999 |
AEB47626.1 | nadD | VAB18032_02710 | VAB18032_28466 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.532 |
folE | lipA | VAB18032_02855 | VAB18032_27441 | COG0302 GTP cyclohydrolase I. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.645 |