| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOO47258.1 | KOO51727.1 | AMD00_21565 | AMD00_04570 | 3-demethylubiquinone-9 3-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.471 |
| KOO48048.1 | KOO51727.1 | AMD00_20830 | AMD00_04570 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.436 |
| KOO48048.1 | KOO52575.1 | AMD00_20830 | AMD00_00365 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.613 |
| KOO48048.1 | glyA | AMD00_20830 | AMD00_15435 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.931 |
| KOO49451.1 | KOO51727.1 | AMD00_13875 | AMD00_04570 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.507 |
| KOO49564.1 | KOO51727.1 | AMD00_14540 | AMD00_04570 | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.424 |
| KOO49564.1 | KOO52575.1 | AMD00_14540 | AMD00_00365 | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
| KOO49564.1 | glyA | AMD00_14540 | AMD00_15435 | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.446 |
| KOO50025.1 | KOO51727.1 | AMD00_17180 | AMD00_04570 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.537 |
| KOO50025.1 | KOO52575.1 | AMD00_17180 | AMD00_00365 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.718 |
| KOO50025.1 | glyA | AMD00_17180 | AMD00_15435 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.532 |
| KOO51595.1 | KOO51727.1 | AMD00_03760 | AMD00_04570 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.400 |
| KOO51727.1 | KOO47258.1 | AMD00_04570 | AMD00_21565 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-demethylubiquinone-9 3-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.471 |
| KOO51727.1 | KOO48048.1 | AMD00_04570 | AMD00_20830 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.436 |
| KOO51727.1 | KOO49451.1 | AMD00_04570 | AMD00_13875 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.507 |
| KOO51727.1 | KOO49564.1 | AMD00_04570 | AMD00_14540 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.424 |
| KOO51727.1 | KOO50025.1 | AMD00_04570 | AMD00_17180 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.537 |
| KOO51727.1 | KOO51595.1 | AMD00_04570 | AMD00_03760 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.400 |
| KOO51727.1 | KOO52071.1 | AMD00_04570 | AMD00_06550 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.457 |
| KOO51727.1 | KOO52575.1 | AMD00_04570 | AMD00_00365 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.518 |