STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTO0135Serine/threonine protein kinase. (1205 aa)    
Predicted Functional Partners:
PTO0456
Cell division cycle protein 48.
   
 0.842
PTO0637
Peptidyl-prolyl cis-trans isomerase.
 
 
 0.837
PTO0232
Pantothenate kinase.
   
 0.811
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.811
dnaK
Chaperone protein Dank; Acts as a chaperone.
   
 0.779
PTO0519
Hypothetical protein.
   
 0.747
PTO0620
ATP (GTP)-binding protein.
   
 0.747
smc
Chromosome partition protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
 0.734
PTO0288
Putative serine/threonine protein phosphatase.
 
 
 0.732
PTO1092
Serine/threonine protein phosphatase.
 
 
 0.729
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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