STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTO0147(S)-2-hydroxy-acid oxidase, iron-sulfur chain. (399 aa)    
Predicted Functional Partners:
PTO0146
(S)-2-hydroxy-acid oxidase chain D.
 
 
 0.905
PTO1486
Anaerobic glycerol-3-phosphate dehydrogenase subunit A.
  
 
 0.867
PTO0997
Succinate dehydrogenase, subunit C.
 
 
 0.851
PTO0995
Succinate dehydrogenase flavoprotein subunit.
    
 0.835
PTO0402
Iron-sulfur cluster-binding protein.
 
 
 0.799
PTO1003
succinyl-CoA synthetase beta chain.
  
 
 0.796
PTO1039
Formate dehydrogenase alpha chain.
  
 
 0.791
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.779
PTO1479
NADH dehydrogenase.
  
 
 0.765
PTO1227
Sulfide dehydrogenase (flavocytochrome C).
 
 
 0.733
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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