Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PTO0152ATPases of the PP-loop superamily. (312 aa)    
Predicted Functional Partners:
thiI
Hypothetical thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 
 0.980
PTO1059
Molybdopterin (MPT) converting factor, subunit 2.
    
 0.811
PTO1341
protein-L-isoaspartate O-methyltransferase.
 
  
 0.810
PTO1133
Rieske iron-sulfur protein.
   
  0.778
PTO0232
Pantothenate kinase.
   
 
  0.773
PTO0521
Molybdopterin biosynthesis MoeB protein.
 
 
 0.762
rps28e
Small subunit ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family.
     
  0.759
PTO1304
Cytochrome c oxidase polypeptide I/III; Belongs to the heme-copper respiratory oxidase family.
     
  0.759
PTO1306
Cytochrome c oxidase polypeptide II.
     
  0.759
PTO1134
Cytochrome b.
    
  0.731
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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