Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO01692-methylcitrate-synthase. (365 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.992
PTO0935
Aconitate hydratase.
  
 0.990
PTO0171
2-methylisocitrate synthase.
 
 
 0.986
PTO0170
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
 
 0.980
PTO0168
Isocitrate dehydrogenase [NADP].
  
 0.979
PTO1003
succinyl-CoA synthetase beta chain.
  
 0.958
PTO0547
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.935
PTO0996
Succinate dehydrogenase iron-sulfur protein.
  
 0.914
PTO0426
Isocitrate dehydrogenase [NADP].
  
 0.872
PTO0995
Succinate dehydrogenase flavoprotein subunit.
  
 0.838
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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