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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Score
PTO0170Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (284 aa)    
Predicted Functional Partners:
PTO0171
2-methylisocitrate synthase.
 
  
 0.993
PTO0169
2-methylcitrate-synthase.
 
 0.980
PTO0935
Aconitate hydratase.
  
 0.956
PTO0889
Citrate synthase.
 
 0.948
PTO0283
Acetyl-coenzyme A synthetase.
  
 
 0.936
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.925
PTO0383
Beta-ketoacyl synthase; Thiolase.
  
 
 0.919
PTO1188
Beta-ketoacyl synthase; Thiolase.
  
 
 0.919
PTO1505
acetyl-CoA acetyltransferase.
  
 
 0.919
PTO1003
succinyl-CoA synthetase beta chain.
  
 
 0.917
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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