Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO01712-methylisocitrate synthase. (425 aa)    
Predicted Functional Partners:
PTO0170
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
 
  
 0.993
PTO0169
2-methylcitrate-synthase.
 
 
 0.986
PTO0889
Citrate synthase.
  
 
 0.941
PTO0935
Aconitate hydratase.
  
 
 0.871
PTO0168
Isocitrate dehydrogenase [NADP].
  
  
 0.819
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 
  0.673
PTO0632
acyl-CoA transferases/carnitine dehydratase.
  
 
  0.568
PTO0172
Acetamidase/formamidase family protein.
       0.554
PTO0816
Adenylosuccinate lyase.
    
 0.548
PTO1462
Glutamate synthase [NADPH] large chain fragment II.
 
  
  0.526
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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