| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0129 | nadE | PTO0129 | PTO0986 | Nicotinamide-nucleotide adenylyltransferase. | NAD synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.961 |
| PTO0129 | nadK | PTO0129 | PTO0193 | Nicotinamide-nucleotide adenylyltransferase. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.920 |
| PTO0190 | PTO0192 | PTO0190 | PTO0192 | Conserved hypothetical protein. | Mov34/MPN/PAD-1 family. | 0.773 |
| PTO0190 | nadK | PTO0190 | PTO0193 | Conserved hypothetical protein. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.793 |
| PTO0190 | pelA | PTO0190 | PTO0189 | Conserved hypothetical protein. | Predicted RNA-binding protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. | 0.878 |
| PTO0190 | ubiX | PTO0190 | PTO0191 | Conserved hypothetical protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.835 |
| PTO0192 | PTO0190 | PTO0192 | PTO0190 | Mov34/MPN/PAD-1 family. | Conserved hypothetical protein. | 0.773 |
| PTO0192 | nadK | PTO0192 | PTO0193 | Mov34/MPN/PAD-1 family. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.935 |
| PTO0192 | pelA | PTO0192 | PTO0189 | Mov34/MPN/PAD-1 family. | Predicted RNA-binding protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. | 0.830 |
| PTO0192 | ubiX | PTO0192 | PTO0191 | Mov34/MPN/PAD-1 family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.773 |
| PTO0523 | nadK | PTO0523 | PTO0193 | Oxidoreductase; GFO/IDH/MocA family. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.748 |
| PTO0546 | PTO0887 | PTO0546 | PTO0887 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase. | 0.904 |
| PTO0546 | nadK | PTO0546 | PTO0193 | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.822 |
| PTO0887 | PTO0546 | PTO0887 | PTO0546 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.904 |
| PTO0887 | nadK | PTO0887 | PTO0193 | Dihydrolipoamide dehydrogenase. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.710 |
| gap | nadK | PTO0742 | PTO0193 | Glyceraldehyde 3-phosphate dehydrogenase. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.720 |
| nadE | PTO0129 | PTO0986 | PTO0129 | NAD synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinamide-nucleotide adenylyltransferase. | 0.961 |
| nadE | nadK | PTO0986 | PTO0193 | NAD synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.940 |
| nadK | PTO0129 | PTO0193 | PTO0129 | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Nicotinamide-nucleotide adenylyltransferase. | 0.920 |
| nadK | PTO0190 | PTO0193 | PTO0190 | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Conserved hypothetical protein. | 0.793 |