| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0374 | PTO0405 | PTO0374 | PTO0405 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | Protein translation initiation factor 2 subunit alpha; IF-2a. | 0.818 |
| PTO0374 | rpl13 | PTO0374 | PTO0323 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | Large subunit ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.855 |
| PTO0374 | rps15 | PTO0374 | PTO0244 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | Small subunit ribosomal protein S15P. | 0.999 |
| PTO0374 | rps19e | PTO0374 | PTO0203 | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | Small subunit ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. | 0.553 |
| PTO0405 | PTO0374 | PTO0405 | PTO0374 | Protein translation initiation factor 2 subunit alpha; IF-2a. | O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr prot [...] | 0.818 |
| PTO0405 | eif1a | PTO0405 | PTO0253 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Protein translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.999 |
| PTO0405 | rpl13 | PTO0405 | PTO0323 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Large subunit ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.846 |
| PTO0405 | rpl18e | PTO0405 | PTO0322 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Large subunit ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | 0.637 |
| PTO0405 | rpl21e | PTO0405 | PTO0389 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Large subunit ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.846 |
| PTO0405 | rpl31e | PTO0405 | PTO0206 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Large subunit ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. | 0.623 |
| PTO0405 | rpl37ae | PTO0405 | PTO0392 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Large subunit ribosomal protein L37AE; Binds to the 23S rRNA. | 0.563 |
| PTO0405 | rps15 | PTO0405 | PTO0244 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Small subunit ribosomal protein S15P. | 0.999 |
| PTO0405 | rps19e | PTO0405 | PTO0203 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Small subunit ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. | 0.999 |
| PTO0405 | rps9 | PTO0405 | PTO0324 | Protein translation initiation factor 2 subunit alpha; IF-2a. | Small subunit ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. | 0.998 |
| eif1a | PTO0405 | PTO0253 | PTO0405 | Protein translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Protein translation initiation factor 2 subunit alpha; IF-2a. | 0.999 |
| eif1a | rpl13 | PTO0253 | PTO0323 | Protein translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Large subunit ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.945 |
| eif1a | rpl18e | PTO0253 | PTO0322 | Protein translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Large subunit ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. | 0.947 |
| eif1a | rpl21e | PTO0253 | PTO0389 | Protein translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Large subunit ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.954 |
| eif1a | rpl31e | PTO0253 | PTO0206 | Protein translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Large subunit ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. | 0.948 |
| eif1a | rpl37ae | PTO0253 | PTO0392 | Protein translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Large subunit ribosomal protein L37AE; Binds to the 23S rRNA. | 0.739 |
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