| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PTO0123 | PTO0261 | PTO0123 | PTO0261 | Purine nucleoside phosphorylase. | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.763 |
| PTO0123 | PTO0942 | PTO0123 | PTO0942 | Purine nucleoside phosphorylase. | 5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. | 0.867 |
| PTO0125 | PTO0261 | PTO0125 | PTO0261 | phenylalanyl-tRNA synthetase alpha chain. | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.657 |
| PTO0125 | PTO0592 | PTO0125 | PTO0592 | phenylalanyl-tRNA synthetase alpha chain. | Translation initiation factor eIF-2, subunit gamma. | 0.697 |
| PTO0125 | PTO0845 | PTO0125 | PTO0845 | phenylalanyl-tRNA synthetase alpha chain. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.410 |
| PTO0125 | hisS | PTO0125 | PTO0512 | phenylalanyl-tRNA synthetase alpha chain. | histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.774 |
| PTO0219 | PTO0261 | PTO0219 | PTO0261 | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.684 |
| PTO0219 | PTO0668 | PTO0219 | PTO0668 | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Nop56p-related protein; Ribosomal biogenesis. | 0.496 |
| PTO0261 | PTO0123 | PTO0261 | PTO0123 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Purine nucleoside phosphorylase. | 0.763 |
| PTO0261 | PTO0125 | PTO0261 | PTO0125 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | phenylalanyl-tRNA synthetase alpha chain. | 0.657 |
| PTO0261 | PTO0219 | PTO0261 | PTO0219 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | GTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.684 |
| PTO0261 | PTO0592 | PTO0261 | PTO0592 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Translation initiation factor eIF-2, subunit gamma. | 0.590 |
| PTO0261 | PTO0668 | PTO0261 | PTO0668 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Nop56p-related protein; Ribosomal biogenesis. | 0.705 |
| PTO0261 | PTO0845 | PTO0261 | PTO0845 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.687 |
| PTO0261 | PTO0942 | PTO0261 | PTO0942 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. | 0.959 |
| PTO0261 | PTO1347 | PTO0261 | PTO1347 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | L-fuculose phosphate aldolase. | 0.985 |
| PTO0261 | hisS | PTO0261 | PTO0512 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.596 |
| PTO0261 | rpoH | PTO0261 | PTO0260 | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.565 |
| PTO0592 | PTO0125 | PTO0592 | PTO0125 | Translation initiation factor eIF-2, subunit gamma. | phenylalanyl-tRNA synthetase alpha chain. | 0.697 |
| PTO0592 | PTO0261 | PTO0592 | PTO0261 | Translation initiation factor eIF-2, subunit gamma. | Archaeal protein translation initiation factor 2B subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.590 |