Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO0273Hypothetical membrane spanning protein. (571 aa)    
Predicted Functional Partners:
guaAA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.684
PTO0465
Orotate phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
     0.673
PTO0274
Glycosyltransferase.
       0.664
PTO0275
Metal dependent hydrolase.
       0.664
PTO0985
Hypothetical membrane protein; Involved in the biosynthesis of polysaccharides.
  
     0.654
PTO1356
Diphosphomevalonate decarboxylase; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5- phosphate. Also able to catalyze the formation of isobutene via the conversion of 3-hydroxyisovalerate (3-HIV) to an unstable 3-phosphate intermediate that undergoes a spontaneous decarboxylation.
  
     0.611
adkA
Adenylate kinase; Belongs to the archaeal adenylate kinase family.
  
     0.596
PTO1419
Replication factor-A protein 1.
  
     0.571
PTO1418
Hypothetical protein.
  
     0.563
tbp
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
 
   
 0.558
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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