Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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PTO0332Succinate-semialdehyde dehydrogenase [NADP+]; NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes. (493 aa)    
Predicted Functional Partners:
PTO0791
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.940
PTO0995
Succinate dehydrogenase flavoprotein subunit.
  
 0.911
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.853
PTO1026
2-keto-3-deoxy gluconate aldolase.
  
 
 0.849
PTO0168
Isocitrate dehydrogenase [NADP].
  
 0.837
PTO1000
2-oxoglutarate synthase, alpha chain.
   
 0.828
PTO1360
Pyruvate ferredoxin oxidoreductase, alpha chain.
   
 0.828
PTO1279
Dihydrodipicolinate synthase; Involved in the degradation of glucose via the Entner- Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy- 6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2- keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3- deoxygalactonate (KDGal). It is equally active with both D- and L- glyceraldehyde; Belongs to the DapA family. KDPG aldolase subfamily.
  
 
 0.827
PTO0999
2-oxoglutarate synthase, beta chain.
    
 0.811
PTO1361
Pyruvate ferredoxin oxidoreductase, beta chain.
    
 0.811
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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