Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO0345Tryptophan synthase alpha chain. (245 aa)    
Predicted Functional Partners:
trpC
Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 
 0.999
PTO0341
Anthranilate synthase component II.
 
 
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.999
PTO0342
Anthranilate synthase component I.
 
  
 0.998
trpF
N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
 
 0.995
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 0.983
PTO0141
Tryptophan synthase beta chain.
   
 0.929
PTO0238
Threonine dehydratase.
  
 
 0.924
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.912
PTO0858
Serine hydroxymethyltransferase.
     
 0.910
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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