Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO0427Fumarate hydratase. (455 aa)    
Predicted Functional Partners:
PTO0995
Succinate dehydrogenase flavoprotein subunit.
 
 
 0.983
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
    
 0.953
PTO1109
Aspartate aminotransferase.
    
 0.946
PTO0425
Asparaginase.
    
 0.945
PTO0957
Malate oxidoreductase.
  
 
 0.917
PTO0996
Succinate dehydrogenase iron-sulfur protein.
  
 
 0.911
PTO0531
Argininosuccinate lyase.
     
 0.904
PTO0816
Adenylosuccinate lyase.
     
 0.896
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.892
PTO1047
Glutamine-hydrolyzing asparagine synthase.
     
 0.891
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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