Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTO0434Hypothetical transmembrane protein DUF 373. (367 aa)    
Predicted Functional Partners:
mptE
Hypothetical protein DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP).
 
     0.969
PTO0700
Hypothetical phosphoserine phosphatase.
 
     0.735
PTO0616
Endonuclease IV.
       0.684
PTO0955
Conserved hypothetical protein DUF51.
       0.684
priL
DNA primase 58 kDa subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
 
     0.647
PTO0942
5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
       0.627
PTO1098
Putative ICC-like phosphoesterases.
  
     0.593
PTO0433
Hypothetical protein.
       0.587
cdc6
Origin recognition complex subunit; Involved in regulation of DNA replication.
  
     0.570
PTO1517
Hypothetical transcriptional regulator.
 
     0.566
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.