Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTO0467Hypothetical ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (274 aa)    
Predicted Functional Partners:
PTO1405
NADH-quinone oxidoreductase chain I.
  
 
 0.804
PTO1403
NADH-quinone oxidoreductase chain D.
     
 0.760
PTO1402
NADH-quinone oxidoreductase chain C.
     
 0.743
PTO1401
NADH-quinone oxidoreductase chain B; Belongs to the complex I 20 kDa subunit family.
     
 0.705
PTO0464
Asymmetrical bis(5'-nucleosyl)-tetraphosphatase.
  
  
 0.676
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.590
PTO0465
Orotate phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.585
lysS
lysyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.585
PTO0128
DNA polymerase delta catalytic subunit.
    
 0.551
dnaK
Chaperone protein Dank; Acts as a chaperone.
   
 0.550
Your Current Organism:
Picrophilus torridus
NCBI taxonomy Id: 263820
Other names: P. torridus DSM 9790, Picrophilus torridus DSM 9790, Picrophilus torridus DSM9790, Picrophilus torridus str. DSM 9790, Picrophilus torridus strain DSM 9790
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